Month: January 2012

Med Adherence – Difference between prescribed and dosing histories [Article]

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Annual Review of Pharmacology and Toxicology (2012 Feb 10;52:275-301. Epub 2011 Sep 19) – No big surprise here, but check out the graphs (posted below), especially the second one where you can see the effect poor compliance/adherence has on therapeutic concentration. Crazy.

Abstract

Satisfactory adherence to aptly prescribed medications is essential for good outcomes of patient care and reliable evaluation of competing modes of drug treatment. The measure of satisfactory adherence is a dosing history that includes timely initiation of dosing plus punctual and persistent execution of the dosing regimen throughout the specified duration of treatment. Standardized terminology for initiation, execution, and persistence of drug dosing is essential for clarity of communication and scientific progress. Electronic methods for compiling drug dosing histories are now the recognized standard for quantifying adherence, the parameters of which support model-based, continuous projections of drug actions and concentrations in plasma that are confirmable by intermittent, direct measurements at single time points. The frequency of inadequate adherence is usually underestimated by pre-electronic methods and thus is clinically unrecognized as a frequent cause of failed treatment or underestimated effectiveness. Intermittent lapses in dosing are potential sources of toxicity through hazardous rebound effects or recurrent first-dose effects.

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Surprise! Pharma says their “digital resources” are good for consumers

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Sirensong Reliance on pharma-sponsored digital resources among online U.S. adults is significant. The research found “51% of online U.S. adults (ages 18+) use pharma-sponsored digital resources, such as condition and treatment information, disease management tools, doctor discussion guides, or mobile apps or websites.” This validates that the interactive information and tools produced by biopharma are … Read more

Digital edition of U.S. Pharmacist off to a bad start

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I received the announcement below in my email just a short time ago. So being the good little pharmacist that I am, I headed on over to the U.S. Pharmacist website to check it out. Imagine my surprise when I clicked on the digital issue link and was greeted with a “Service Unavailable” message (bottom image). Bummer. Hopefully they’ll get it up and running shortly.

Update: Looks like they got it working within 5 minutes of me posting this. It’s a nice format. Check it out for yourself here.

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Impact of Anti-infective Drug Shortages [Article]

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Clinical Infectious Disease (online January 19): Abstract Anti-infective shortages pose significant logistical and clinical challenges to hospitals and may be considered a public health emergency. Anti-infectives often represent irreplaceable life-saving treatments. Furthermore, few new agents are available to treat increasingly prevalent multidrug-resistant pathogens. Frequent anti-infective shortages have substantially altered patient care and may lead to … Read more

Domain expertise in healthcare can go a long way

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mobilehealthnews: “[John] Sculley said [while speaking at the Digital Health Summit, CES 2012] that some companies have put too much emphasis on style over substance. “The thing that is missing is getting the people with the domain expertise aligned with the people with technological know-how to turn ideas into branded services,”” I think these comments … Read more

Contact lenses loaded with anesthetic medication

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When I think of technological advances these are the things that come to mind. medGadget “…researchers at University of Florida are reporting that they developed a way to load topical anesthetics into contact lenses to provide extended delivery of pain relief in a uniform fashion.  And since many of the patients that undergo eye procedures … Read more

If I were to buy a tablet today…

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imageI’m always on the lookout for a new tablet, and never more so then I am at this moment. My trusty Lenovo X201T is getting old. At more than a year, it’s downright ancient in computer technology years. It’s a dilemma to be sure.

Fortunately for me there’s no shortage of tablets on the market: Windows OS, Android OS, iOS. Crud, based on reports from CES 2012 I’ll have a much bigger selection within another 6 months or so.

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